Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50287810
Substrate
n/a
Meas. Tech.
ChEBML_46464
Ki
6680±n/a nM
Citation
 Gallant, M; Dufresne, C; Gareau, Y; Guay, D; Leblanc, Y; Prasit, P; Rochette, C; Sawyer, N; Slipetz, DM; Tremblay, N; Metters, KM; Labelle, M New class of potent ligands for the human peripheral cannabinoid receptor Bioorg Med Chem Lett 6:2263-2268 (1996)    Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50287810
Synonyms:
2-Methyl-3-morpholin-4-ylmethyl-1-naphthalen-1-yl-1H-indole | CHEMBL421685
Type:
Small organic molecule
Emp. Form.:
C24H24N2O
Mol. Mass.:
356.4602
SMILES:
Cc1c(CN2CCOCC2)c2ccccc2n1-c1cccc2ccccc12 |(8.88,-12.23,;7.56,-11.48,;7.56,-9.94,;8.81,-8.69,;10.5,-9.14,;10.55,-10.88,;12.08,-11.73,;13.57,-10.81,;13.54,-9.05,;11.98,-8.22,;4.9,-9.94,;3.59,-9.15,;2.26,-9.92,;2.26,-11.48,;3.59,-12.23,;4.9,-11.48,;6.23,-12.24,;6.25,-13.77,;7.58,-14.53,;7.58,-16.1,;6.25,-16.86,;4.9,-16.1,;3.57,-16.86,;2.23,-16.1,;2.23,-14.56,;3.57,-13.77,;4.9,-14.56,)|
Structure:
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