Reaction Details Report a problem with these data
Target
Subtilisin BL
Ligand
BDBM50288130
Substrate
n/a
Meas. Tech.
ChEMBL_197707 (CHEMBL801819)
Ki
986000±n/a nM
Citation
 Stabile, MR; Lai, WG; DeSantis, G; Gold, M; Jones, JB; Mitchinson, C; Bott, RR; Graycar, TP; Liu, CC Probing the specificity of the S1 binding site of M222 mutants of subtilisin B. lentus with boronic acid inhibitors Bioorg Med Chem Lett 6:2501-2506 (1996)    Article 
Target
Name:
Subtilisin BL
Synonyms:
SUBB_LEDLE | Subtilisin
Type:
PROTEIN
Mol. Mass.:
26829.89
Organism:
Bacillus lentus
Description:
ChEMBL_197707
Residue:
269
Sequence:
AQSVPWGISRVQAPAAHNRGLTGSGVKVAVLDTGISTHPDLNIRGGASFVPGEPSTQDGNGHGTHVAGTIAALNNSIGVLGVAPSAELYAVKVLGADGRGAISSIAQGLEWAGNNGMHVANLSLGSPSPSATLEQAVNSATSRGVLVVAASGNSGASSISYPARYANAMAVGATDQNNNRASFSQYGAGLDIVAPGVNVQSTYPGSTYASLNGTSMATPHVAGAAALVKQKNPSWSNVQIRNHLKNTATSLGSTNLYGSGLVNAEAATR
  
Inhibitor
Name:
BDBM50288130
Synonyms:
Boronic acid derivative | CHEMBL79870
Type:
Small organic molecule
Emp. Form.:
C9H13BO3
Mol. Mass.:
180.009
SMILES:
COc1ccc(CCB(O)O)cc1
Structure:
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