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Target
Chymotrypsin-like protease CTRL-1
Ligand
BDBM50288609
Substrate
n/a
Meas. Tech.
ChEBML_49606
IC50
22.0±n/a nM
Citation
 Iqbal, M; Chatterjee, S; Kauer, JC; Mallamo, JP; Messina, PA; Reiboldt, A; Siman, R Potent α-ketocarbonyl and boronic ester derived inhibitors of proteasome Bioorg Med Chem Lett 6:287-290 (1996)    Article 
Target
Name:
Chymotrypsin-like protease CTRL-1
Synonyms:
CTRL | CTRL1 | CTRL_HUMAN
Type:
PROTEIN
Mol. Mass.:
28008.18
Organism:
Homo sapiens (Human)
Description:
ChEMBL_49606
Residue:
264
Sequence:
MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFSTWINQVIAYN
  
Inhibitor
Name:
BDBM50288609
Synonyms:
Alpha-ketocarbonyl derivative | CHEMBL317337
Type:
Small organic molecule
Emp. Form.:
C31H54N8O6
Mol. Mass.:
634.8105
SMILES:
CCNC(=O)C(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N[N+]([O-])=O)NC(=O)C(CCCCCCCCC#N)C1CCCC1 |w:19.18|
Structure:
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