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Target
Chymotrypsin-like protease CTRL-1
Ligand
BDBM50031442
Substrate
n/a
Meas. Tech.
ChEBML_49606
IC50
2±n/a nM
Citation
 Iqbal, M; Chatterjee, S; Kauer, JC; Mallamo, JP; Messina, PA; Reiboldt, A; Siman, R Potent α-ketocarbonyl and boronic ester derived inhibitors of proteasome Bioorg Med Chem Lett 6:287-290 (1996)    Article 
Target
Name:
Chymotrypsin-like protease CTRL-1
Synonyms:
CTRL | CTRL1 | CTRL_HUMAN
Type:
PROTEIN
Mol. Mass.:
28008.18
Organism:
Homo sapiens (Human)
Description:
ChEMBL_49606
Residue:
264
Sequence:
MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFSTWINQVIAYN
  
Inhibitor
Name:
BDBM50031442
Synonyms:
1N-[4-amino(nitroimino)methylamino-1-(1-formyl-3-methylbutylcarbamoyl)butyl]-2-cyclopentyl-10-(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)decanamide | Alpha-ketocarbonyl derivative | CHEMBL307387
Type:
Small organic molecule
Emp. Form.:
C35H53N7O7
Mol. Mass.:
683.838
SMILES:
CC(C)CC(NC(=O)C(CCCN=C(N)N[N+]([O-])=O)NC(=O)C(CCCCCCCCN1C(=O)c2ccccc2C1=O)C1CCCC1)C=O |w:12.11|
Structure:
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