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Target
Protein kinase C eta type
Ligand
BDBM50064089
Substrate
n/a
Meas. Tech.
ChEBML_161130
Ki
0.100000±n/a nM
Citation
 Irie, K; Yanai, Y; Ohigashi, H; Wender, PA; Miller, BL Synthesis and characterization of the second cysteine-rich region of mouse skin PKCGh Bioorg Med Chem Lett 6:353-356 (1996)    Article 
Target
Name:
Protein kinase C eta type
Synonyms:
KPCL_MOUSE | Pkch | Prkch | Protein kinase C eta
Type:
PROTEIN
Mol. Mass.:
77933.38
Organism:
Mus musculus
Description:
ChEMBL_161130
Residue:
683
Sequence:
MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTKQKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTAGTSDTFEGWVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQVNGHKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDAKIAEQRFGINIPHKFNVHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGLQPGNISPTSKLISRSTLRRQGKEGSKEGNGIGVNSSSRFGIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHEKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSLTQGGEHEILRHPFFKEIDWAQLNHRQLEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPELQL
  
Inhibitor
Name:
BDBM50064089
Synonyms:
4-hydroxymethyl-7,10-diisopropyl-8,10,13-trimethyl-13-vinyl-(4S,7S,10R,13R)-3,4,5,6,7,8,10,11,12,13-decahydro-1H-benzo[g][1,4]diazonino[7,6,5-cd]indol-6-one | CHEMBL417692 | teleocidin B-4 | telocidinB-4 4-hydroxymethyl-7,10-diisopropyl-8,10,13-trimethyl-13-vinyl-(4S,7S,10R,13R)-3,4,5,6,7,8,10,11,12,13-decahydro-1H-benzo[g][1,4]diazonino[7,6,5-cd]indol-6-one
Type:
Small organic molecule
Emp. Form.:
C28H41N3O2
Mol. Mass.:
451.644
SMILES:
CC(C)[C@@H]1N(C)c2cc3c(c4[nH]cc(C[C@@H](CO)NC1=O)c24)[C@](C)(CC[C@]3(C)C(C)C)C=C |r|
Structure:
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