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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM22
Substrate
n/a
Meas. Tech.
ChEBML_79473
Ki
0.250000±n/a nM
Citation
 Dax, SL; Cook, SC Cyclic urea HIV protease inhibitors containing alkynyl- and alkenyl-tethered heterocycles in the P2 region Bioorg Med Chem Lett 6:797-802 (1996)    Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM22
Synonyms:
(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis[(2E)-3-(1H-pyrazol-4-yl)prop-2-en-1-yl]-1,3-diazepan-2-one | DMPC Cyclic Urea 2
Type:
n/a
Emp. Form.:
C31H34N6O3
Mol. Mass.:
538.6401
SMILES:
O[C@@H]1[C@@H](O)[C@@H](Cc2ccccc2)N(C\C=C\c2cn[nH]c2)C(=O)N(C\C=C\c2cn[nH]c2)[C@@H]1Cc1ccccc1
Structure:
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