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Target
MHC class II antigen
Ligand
BDBM50289290
Substrate
n/a
Meas. Tech.
ChEMBL_192856 (CHEMBL799390)
IC50
>50000±n/a nM
Citation
 Cunningham, BR; Rivetna, M; Tolman, RL; Flattery, SJ; Nichols, EA; Schwartz, CD; Wicker, LS; Hermes, JD; Jones, AB SAR for MHC class II binding tetrapeptides: Correlation with potential binding site Bioorg Med Chem Lett 7:19-24 (1997)    Article 
Target
Name:
MHC class II antigen
Synonyms:
DR-1 | DR1 | HLA class II histocompatibility antigen DRB1-1 | HLA class II histocompatibility antigen, DRB1-1 beta chain | Human leukocyte antigen DR beta chain | MHC class I antigen DRB1*1
Type:
PROTEIN
Mol. Mass.:
29917.79
Organism:
Homo sapiens (Human)
Description:
ChEMBL_192854
Residue:
266
Sequence:
MVCLKLPGGSCMTALTVTLMVLSSPLALAGDTRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS
  
Inhibitor
Name:
BDBM50289290
Synonyms:
(S)-3-{(S)-2-[(S)-2-((S)-2-Ethoxycarbonylamino-3-phenyl-propionylamino)-3-methyl-butyrylamino]-propionylamino}-succinamic acid | CHEMBL418908
Type:
Small organic molecule
Emp. Form.:
C24H35N5O8
Mol. Mass.:
521.5634
SMILES:
CCOC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(N)=O
Structure:
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