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Target
Peptidylprolyl isomerase
Ligand
BDBM50068573
Substrate
n/a
Meas. Tech.
ChEBML_66431
Ki
3±n/a nM
Citation
 Hamilton, GS; Huang, W; Connolly, MA; Ross, DT; Guo, H; Valentine, HL; Suzdak, PD; Steiner, JP FKBP12-binding domain analogues of FK506 are potent, nonimmunosuppressive neurotrophic agents in vitro and promote recovery in a mouse model of parkinson's disease Bioorg Med Chem Lett 7:1785-1790 (1997)    Article 
Target
Name:
Peptidylprolyl isomerase
Synonyms:
FK506 binding protein 12
Type:
PROTEIN
Mol. Mass.:
11960.67
Organism:
Gallus gallus
Description:
ChEMBL_66431
Residue:
108
Sequence:
MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFRFKIGRQEVIKGFEEGVTQMSLGQRAKLTCTPEMAYGATGHPGVIPPNATLLFDVELLRLE
  
Inhibitor
Name:
BDBM50068573
Synonyms:
1-(2-Oxo-2-phenyl-acetyl)-piperidine-2-carboxylic acid 4-phenyl-1-(3-phenyl-propyl)-butyl ester | CHEMBL300752
Type:
Small organic molecule
Emp. Form.:
C33H37NO4
Mol. Mass.:
511.6512
SMILES:
O=C(OC(CCCc1ccccc1)CCCc1ccccc1)C1CCCCN1C(=O)C(=O)c1ccccc1
Structure:
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