Target
Genome polyprotein
Ligand
BDBM50289949
Substrate
n/a
Meas. Tech.
ChEMBL_158974 (CHEMBL763741)
IC50
2400±n/a nM
Citation
 Abood, NASchretzman, LAFlynn, DLHouseman, KAWittwer, AJDilworth, VMHippenmeyer, PJHolwerda, BC Inhibition of human cytomegalovirus protease by benzoxazinones and evidence of antiviral activity in cell culture Bioorg Med Chem Lett 7:2105-2108 (1997)    Article 
Target
Name:
Genome polyprotein
Synonyms:
Human rhinovirus A protease | Human rhinovirus B 3A protease
Type:
PROTEIN
Mol. Mass.:
44361.04
Organism:
Human rhinovirus B
Description:
ChEMBL_158953
Residue:
401
Sequence:
AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMSAIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIANIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVITTGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDRNEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYNYPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQTIHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
  
Inhibitor
Name:
BDBM50289949
Synonyms:
CHEMBL303802 | N-[5-Methyl-4-oxo-2-(1-phenyl-ethylamino)-4H-benzo[d][1,3]oxazin-6-yl]-2-pyrrolidin-1-yl-acetamide
Type:
Small organic molecule
Emp. Form.:
C23H26N4O3
Mol. Mass.:
406.4775
SMILES:
C[C@@H](Nc1nc2ccc(NC(=O)CN3CCCC3)c(C)c2c(=O)o1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: