Reaction Details Report a problem with these data
Target
Genome polyprotein
Ligand
BDBM50063719
Substrate
n/a
Meas. Tech.
ChEBML_158973
IC50
4000±n/a nM
Citation
 Abood, NA; Schretzman, LA; Flynn, DL; Houseman, KA; Wittwer, AJ; Dilworth, VM; Hippenmeyer, PJ; Holwerda, BC Inhibition of human cytomegalovirus protease by benzoxazinones and evidence of antiviral activity in cell culture Bioorg Med Chem Lett 7:2105-2108 (1997)    Article 
Target
Name:
Genome polyprotein
Synonyms:
Human rhinovirus A protease | Human rhinovirus B 3A protease
Type:
PROTEIN
Mol. Mass.:
44361.04
Organism:
Human rhinovirus B
Description:
ChEMBL_158953
Residue:
401
Sequence:
AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMSAIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIANIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVITTGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDRNEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYNYPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQTIHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
  
Inhibitor
Name:
BDBM50063719
Synonyms:
2-Isopropylamino-5-methyl-benzo[d][1,3]oxazin-4-one | CHEMBL10756
Type:
Small organic molecule
Emp. Form.:
C12H14N2O2
Mol. Mass.:
218.2518
SMILES:
CC(C)Nc1nc2cccc(C)c2c(=O)o1
Structure:
Search PDB for entries with ligand similarity: