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Target
Genome polyprotein
Ligand
BDBM50289950
Substrate
n/a
Meas. Tech.
ChEBML_158973
IC50
270±n/a nM
Citation
 Abood, NA; Schretzman, LA; Flynn, DL; Houseman, KA; Wittwer, AJ; Dilworth, VM; Hippenmeyer, PJ; Holwerda, BC Inhibition of human cytomegalovirus protease by benzoxazinones and evidence of antiviral activity in cell culture Bioorg Med Chem Lett 7:2105-2108 (1997)    Article 
Target
Name:
Genome polyprotein
Synonyms:
Human rhinovirus A protease | Human rhinovirus B 3A protease
Type:
PROTEIN
Mol. Mass.:
44361.04
Organism:
Human rhinovirus B
Description:
ChEMBL_158953
Residue:
401
Sequence:
AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMSAIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIANIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVITTGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDRNEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYNYPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQTIHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
  
Inhibitor
Name:
BDBM50289950
Synonyms:
4-Methoxy-N-[5-methyl-4-oxo-2-(1-phenyl-ethylamino)-4H-benzo[d][1,3]oxazin-6-yl]-benzenesulfonamide | CHEMBL63420
Type:
Small organic molecule
Emp. Form.:
C24H23N3O5S
Mol. Mass.:
465.522
SMILES:
COc1ccc(cc1)S(=O)(=O)Nc1ccc2nc(N[C@H](C)c3ccccc3)oc(=O)c2c1C
Structure:
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