Reaction Details Report a problem with these data
Target
Chymotrypsin-C
Ligand
BDBM50291321
Substrate
n/a
Meas. Tech.
ChEMBL_216447 (CHEMBL820162)
IC50
950±n/a nM
Citation
 Potetinova, JV; Voyushina, TL; Stepanov, VM Enzymatic synthesis of peptidyl amino alcohols and peptidyl amino aldehydes-serine proteinase inhibitors Bioorg Med Chem Lett 7:705-710 (1997)    Article 
Target
Name:
Chymotrypsin-C
Synonyms:
CLCR | CTRC | CTRC_HUMAN | Caldecrin | Chymotrypsin | Chymotrypsin C | Chymotrypsin-C
Type:
Enzyme
Mol. Mass.:
29487.98
Organism:
Homo sapiens (Human)
Description:
Q99895
Residue:
268
Sequence:
MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
  
Inhibitor
Name:
BDBM50291321
Synonyms:
CHEMBL163002 | {1-[1-(1-Benzyl-2-oxo-ethylcarbamoyl)-ethylcarbamoyl]-ethyl}-carbamic acid benzyl ester
Type:
Small organic molecule
Emp. Form.:
C23H27N3O5
Mol. Mass.:
425.4776
SMILES:
C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C=O
Structure:
Search PDB for entries with ligand similarity: