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Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM50291550
Substrate
n/a
Meas. Tech.
ChEBML_138345
IC50
412±n/a nM
Citation
 Conti, P; Dallanoce, C; Amici, MD; Micheli, CD; Ebert, B Synthesis and binding affinity of new muscarinic ligands structurally related to oxotremorine Bioorg Med Chem Lett 7:1033-1036 (1997)    Article 
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51390.46
Organism:
RAT
Description:
P08482
Residue:
460
Sequence:
MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM50291550
Synonyms:
3-(4-Pyrrolidin-1-yl-but-2-ynyloxy)-4,5-dihydro-isoxazole | CHEMBL8610
Type:
Small organic molecule
Emp. Form.:
C11H16N2O2
Mol. Mass.:
208.2569
SMILES:
C(OC1=NOCC1)C#CCN1CCCC1 |t:2|
Structure:
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