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Target
Histamine H3 receptor
Ligand
BDBM22911
Substrate
n/a
Meas. Tech.
ChEMBL_577510 (CHEMBL1057862)
Ki
2±n/a nM
Citation
 Mitobe, Y; Ito, S; Mizutani, T; Nagase, T; Sato, N; Tokita, S Development of a selective and potent radioactive ligand for histamine H(3) receptors: A compound potentially useful for receptor occupancy studies. Bioorg Med Chem Lett 19:4075-8 (2009) [PubMed]  Article 
Target
Name:
Histamine H3 receptor
Synonyms:
HH3R | HRH3_MOUSE | Hrh3
Type:
PROTEIN
Mol. Mass.:
48560.37
Organism:
Mus musculus
Description:
ChEMBL_988451
Residue:
445
Sequence:
MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK
  
Inhibitor
Name:
BDBM22911
Synonyms:
2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide | CHEMBL19439 | CHEMBL544911 | Imetit | {[2-(1H-imidazol-4-yl)ethyl]sulfanyl}methanimidamide
Type:
Small organic molecule
Emp. Form.:
C6H10N4S
Mol. Mass.:
170.235
SMILES:
NC(=N)SCCc1cnc[nH]1
Structure:
Search PDB for entries with ligand similarity: