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Target
Vasopressin V1a receptor
Ligand
BDBM50295770
Substrate
n/a
Meas. Tech.
ChEMBL_578146 (CHEMBL1059544)
Ki
2320±n/a nM
Citation
 Brown, A; Ellis, D; Pearce, D; Ralph, M; Sciammetta, N Aryloxypyrazines as highly selective antagonists of Oxytocin. Bioorg Med Chem Lett 19:2634-6 (2009) [PubMed]  Article 
Target
Name:
Vasopressin V1a receptor
Synonyms:
AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
46820.18
Organism:
Homo sapiens (Human)
Description:
P37288
Residue:
418
Sequence:
MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
  
Inhibitor
Name:
BDBM50295770
Synonyms:
2-(4-(6-methoxypyridin-3-yl)-5-methyl-4H-1,2,4-triazol-3-yl)-5-phenoxypyrazine | CHEMBL539665
Type:
Small organic molecule
Emp. Form.:
C19H16N6O2
Mol. Mass.:
360.3693
SMILES:
COc1ccc(cn1)-n1c(C)nnc1-c1cnc(Oc2ccccc2)cn1
Structure:
Search PDB for entries with ligand similarity: