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Target
D(2) dopamine receptor
Ligand
BDBM50298911
Substrate
n/a
Meas. Tech.
ChEMBL_588134 (CHEMBL1044860)
Ki
810±n/a nM
Citation
 Loaiza, PR; Löber, S; Hübner, H; Gmeiner, P Parallel synthesis of potent dopaminergic N-phenyltriazole carboxamides applying a novel click chemistry based phenol linker. Bioorg Med Chem 17:5482-7 (2009) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50298911
Synonyms:
CHEMBL573792 | N-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl}-1-(4-nitrophenyl)-1H-[1,2,3]triazol-4-carboxamide
Type:
Small organic molecule
Emp. Form.:
C23H25Cl2N7O3
Mol. Mass.:
518.396
SMILES:
[O-][N+](=O)c1ccc(cc1)-n1cc(nn1)C(=O)NCCCCN1CCN(CC1)c1cccc(Cl)c1Cl
Structure:
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