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Target
D(3) dopamine receptor
Ligand
BDBM50298914
Substrate
n/a
Meas. Tech.
ChEMBL_588136 (CHEMBL1044862)
Ki
83±n/a nM
Citation
 Loaiza, PR; Löber, S; Hübner, H; Gmeiner, P Parallel synthesis of potent dopaminergic N-phenyltriazole carboxamides applying a novel click chemistry based phenol linker. Bioorg Med Chem 17:5482-7 (2009) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50298914
Synonyms:
CHEMBL572867 | N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-4-(1-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl)butanamide
Type:
Small organic molecule
Emp. Form.:
C27H34Cl2N6O2
Mol. Mass.:
545.504
SMILES:
COc1ccc(cc1)-n1cc(CCCC(=O)NCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)nn1
Structure:
Search PDB for entries with ligand similarity: