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Target
Cell division control protein 42 homolog
Ligand
BDBM25524
Substrate
n/a
Meas. Tech.
ChEMBL_588744 (CHEMBL1053691)
IC50
>100000±n/a nM
Citation
 Beausoleil, E; Chauvignac, C; Taverne, T; Lacombe, S; Pognante, L; Leblond, B; Pallares, D; Oliveira, CD; Bachelot, F; Carton, R; Peillon, H; Coutadeur, S; Picard, V; Lambeng, N; Désiré, L; Schweighoffer, F Structure-activity relationship of isoform selective inhibitors of Rac1/1b GTPase nucleotide binding. Bioorg Med Chem Lett 19:5594-8 (2009) [PubMed]  Article 
Target
Name:
Cell division control protein 42 homolog
Synonyms:
CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa)
Type:
PROTEIN
Mol. Mass.:
21258.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_652970
Residue:
191
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
  
Inhibitor
Name:
BDBM25524
Synonyms:
17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{14,19}]henicosa-1(13),2,4(8),9,11,14(19),15,17,20-nonaen-21-ium | CHEMBL13045 | CHEMBL258893 | Chelerytherine | Toddalin | chelerythrine
Type:
Small organic molecule
Emp. Form.:
C21H18NO4
Mol. Mass.:
348.3714
SMILES:
COc1ccc2c(c[n+](C)c3c4cc5OCOc5cc4ccc23)c1OC
Structure:
Search PDB for entries with ligand similarity: