Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50304634
Substrate
n/a
Meas. Tech.
ChEMBL_604433 (CHEMBL1070689)
Ki
4.83±n/a nM
Citation
 Choi, WJ; Lee, HW; Kim, HO; Chinn, M; Gao, ZG; Patel, A; Jacobson, KA; Moon, HR; Jung, YH; Jeong, LS Design and synthesis of N(6)-substituted-4'-thioadenosine-5'-uronamides as potent and selective human A(3) adenosine receptor agonists. Bioorg Med Chem 17:8003-11 (2009) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50304634
Synonyms:
9-(5'-Ethylaminocarbonyl-4'-thio-beta-D-ribofuranosyl)-N6-methyladenine | CHEMBL611359
Type:
Small organic molecule
Emp. Form.:
C13H18N6O3S
Mol. Mass.:
338.385
SMILES:
CCNC(=O)[C@H]1S[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC)ncnc12 |r|
Structure:
Search PDB for entries with ligand similarity: