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Target
Cannabinoid receptor 2
Ligand
BDBM50304933
Substrate
n/a
Meas. Tech.
ChEMBL_606628 (CHEMBL1071855)
Ki
90±n/a nM
Citation
 Sellitto, I; Le Bourdonnec, B; Worm, K; Goodman, A; Savolainen, MA; Chu, GH; Ajello, CW; Saeui, CT; Leister, LK; Cassel, JA; Dehaven, RN; Labuda, CJ; Koblish, M; Little, PJ; Brogdon, BL; Smith, SA; Dolle, RE Novel sulfamoyl benzamides as selective CB(2) agonists with improved in vitro metabolic stability. Bioorg Med Chem Lett 20:387-91 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50304933
Synonyms:
(S)-N-(3-(3-hydroxypyrrolidin-1-ylsulfonyl)-4,5-dimethylphenyl)-2,2-dimethylbutanamide | CHEMBL591795
Type:
Small organic molecule
Emp. Form.:
C18H28N2O4S
Mol. Mass.:
368.491
SMILES:
CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CC[C@H](O)C1 |r|
Structure:
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