Reaction Details Report a problem with these data
Target
C5a anaphylatoxin chemotactic receptor 1
Ligand
BDBM50305735
Substrate
n/a
Meas. Tech.
ChEMBL_604758 (CHEMBL1072552)
EC50
>60000±n/a nM
Citation
 Chen, JJ; Cole, DC; Ciszewski, G; Crouse, K; Ellingboe, JW; Nowak, P; Tawa, GJ; Berstein, G; Li, W Identification of a new class of small molecule C5a receptor antagonists. Bioorg Med Chem Lett 20:662-4 (2010) [PubMed]  Article 
Target
Name:
C5a anaphylatoxin chemotactic receptor 1
Synonyms:
C5a-R | CD_antigen=CD88 | C5a anaphylatoxin chemotactic receptor | C5AR1_HUMAN | C5AR1 | C5AR | C5R1 | C5a anaphylatoxin chemotactic receptor (C5aR)
Type:
Enzyme
Mol. Mass.:
39347.68
Organism:
Human
Description:
P21730
Residue:
350
Sequence:
MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKTLKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
  
Inhibitor
Name:
BDBM50305735
Synonyms:
N,N'-(1,2-phenylene)bis(N-methyl-1-phenylmethanesulfonamide) | CHEMBL595990
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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