Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50308566
Substrate
n/a
Meas. Tech.
ChEMBL_613657 (CHEMBL1067000)
Ki
4.16±n/a nM
Citation
 Hierrezuelo, J; Manuel López-Romero, J; Rico, R; Brea, J; Isabel Loza, M; Cai, C; Algarra, M Synthesis of theophylline derivatives and study of their activity as antagonists at adenosine receptors. Bioorg Med Chem 18:2081-8 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50308566
Synonyms:
8-(4-(3,6,9,12-tetraoxatricos-22-enyloxy)phenyl)-theophylline | CHEMBL589251
Type:
Small organic molecule
Emp. Form.:
C33H50N4O7
Mol. Mass.:
614.7727
SMILES:
Cn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccc(OCCOCCOCCOCCOCCCCCCCCCCC=C)cc1
Structure:
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