Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50313913
Substrate
n/a
Meas. Tech.
ChEMBL_615496 (CHEMBL1105126)
Ki
>10000±n/a nM
Citation
 Robaa, D; Enzensperger, C; Abul Azm, Sel D; El Khawass, el S; El Sayed, O; Lehmann, J Dopamine receptor ligands. Part 18: (1) modification of the structural skeleton of indolobenzazecine-type dopamine receptor antagonists. J Med Chem 53:2646-50 (2010) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DRD3_HUMAN | DRD3 | Dopamine D3 receptor (D3R) | Dopamine D3 receptor (D3) | Dopamine D3 receptor | DOPAMINE D3 | Dopamine receptor | Dopamine receptor D3 | Dopamine receptor (D3)
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Human
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50313913
Synonyms:
5,6,8,9,10,14c-Hexahydroindolo[3',2':3,4,]pyrido[2,1-a]isoquinoline | CHEMBL1086789
Type:
Small organic molecule
Emp. Form.:
C19 H18 N2
Mol. Mass.:
274.35961
SMILES:
C1Cc2[nH]c3ccccc3c2C2N1CCc1ccccc21
Structure:
Search PDB for entries with ligand similarity: