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Target
D(3) dopamine receptor
Ligand
BDBM50313917
Substrate
n/a
Meas. Tech.
ChEMBL_615496 (CHEMBL1105126)
Ki
42.9±n/a nM
Citation
 Robaa, D; Enzensperger, C; Abul Azm, Sel D; El Khawass, el S; El Sayed, O; Lehmann, J Dopamine receptor ligands. Part 18: (1) modification of the structural skeleton of indolobenzazecine-type dopamine receptor antagonists. J Med Chem 53:2646-50 (2010) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50313917
Synonyms:
6-Methyl-5,6,7,8,13,15-hexahydro-4H-indolo[4,3a,3-fg][3]benzazacycloundecene | CHEMBL1087300
Type:
Small organic molecule
Emp. Form.:
C20H22N2
Mol. Mass.:
290.4021
SMILES:
CN1CCc2ccccc2Cc2c[nH]c3cccc(CC1)c23
Structure:
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