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Target
D(2) dopamine receptor
Ligand
BDBM50313918
Substrate
n/a
Meas. Tech.
ChEMBL_615495 (CHEMBL1105125)
Ki
>10000±n/a nM
Citation
 Robaa, D; Enzensperger, C; Abul Azm, Sel D; El Khawass, el S; El Sayed, O; Lehmann, J Dopamine receptor ligands. Part 18: (1) modification of the structural skeleton of indolobenzazecine-type dopamine receptor antagonists. J Med Chem 53:2646-50 (2010) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50313918
Synonyms:
5-Methyl-4,5,6,7-tetrahydroindolo[4,3a,3-ef][3]benzazecine | CHEMBL1088073
Type:
Small organic molecule
Emp. Form.:
C19H20N2
Mol. Mass.:
276.3755
SMILES:
CN1CCc2ccccc2Cc2c[nH]c3cccc(C1)c23
Structure:
Search PDB for entries with ligand similarity: