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Target
Adenosine receptor A3
Ligand
BDBM50315604
Substrate
n/a
Meas. Tech.
ChEMBL_627569 (CHEMBL1113575)
Ki
2580±n/a nM
Citation
 Pastorin, G; Federico, S; Paoletta, S; Corradino, M; Cateni, F; Cacciari, B; Klotz, KN; Gao, ZG; Jacobson, KA; Spalluto, G; Moro, S Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists: A preliminary inspection of ligand-receptor recognition process. Bioorg Med Chem 18:2524-36 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50315604
Synonyms:
2-(furan-2-yl)-5-(methylthio)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine | CHEMBL1090123
Type:
Small organic molecule
Emp. Form.:
C9H8N6OS
Mol. Mass.:
248.264
SMILES:
CSc1nc(N)n2nc(nc2n1)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: