Reaction Details Report a problem with these data
Target
Adenosylhomocysteinase
Ligand
BDBM50316222
Substrate
n/a
Meas. Tech.
ChEMBL_628342 (CHEMBL1114611)
IC50
30±n/a nM
Citation
 Kim, BG; Chun, TG; Lee, HY; Snapper, ML A new structural class of S-adenosylhomocysteine hydrolase inhibitors. Bioorg Med Chem 17:6707-14 (2009) [PubMed]  Article 
Target
Name:
Adenosylhomocysteinase
Synonyms:
Adenosylhomocysteinase | Ahcy | SAHH_RAT
Type:
PROTEIN
Mol. Mass.:
47537.52
Organism:
Rattus norvegicus
Description:
ChEMBL_1507790
Residue:
432
Sequence:
MADKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHFKDGPLNMILDDGGDLTNLIHTKHPQLLSGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYLLKNGHRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY
  
Inhibitor
Name:
BDBM50316222
Synonyms:
CHEMBL1095280 | D-ERITADENINE | eritadenine
Type:
Small organic molecule
Emp. Form.:
C9H11N5O4
Mol. Mass.:
253.2147
SMILES:
Nc1ncnc2n(C[C@@H](O)[C@@H](O)C(O)=O)cnc12 |r|
Structure:
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