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Target
Virokine/NFkB inhibitor
Ligand
BDBM50316627
Substrate
n/a
Meas. Tech.
ChEMBL_632000 (CHEMBL1108211)
IC50
1300±n/a nM
Citation
 Cheltsov, AV; Aoyagi, M; Aleshin, A; Yu, EC; Gilliland, T; Zhai, D; Bobkov, AA; Reed, JC; Liddington, RC; Abagyan, R Vaccinia virus virulence factor N1L is a novel promising target for antiviral therapeutic intervention. J Med Chem 53:3899-906 (2010) [PubMed]  Article 
Target
Name:
Virokine/NFkB inhibitor
Synonyms:
N1L
Type:
PROTEIN
Mol. Mass.:
13954.85
Organism:
Vaccinia virus
Description:
ChEMBL_631987
Residue:
117
Sequence:
MRTLLIRYILWRNDNDQTYYNDDFKKLMLLDELVDDGDVCTLIKNMRMTLSDGPLLDRLNQPVNNIEDAKRMIAISAKVARDIGERSEIRWEESFTILFRMIETYFDDLMIDLYGEK
  
Inhibitor
Name:
BDBM50316627
Synonyms:
4,4'-(1,2-phenylenebis(azan-1-yl-1-ylidene))bis(methan-1-yl-1-ylidene)dibenzene-1,2-diol | CHEMBL1094497
Type:
Small organic molecule
Emp. Form.:
C20H16N2O4
Mol. Mass.:
348.352
SMILES:
Oc1ccc(\C=N\c2ccccc2\N=C\c2ccc(O)c(O)c2)cc1O
Structure:
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