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Target
Adenosine receptor A1
Ligand
BDBM50316850
Substrate
n/a
Meas. Tech.
ChEMBL_632846 (CHEMBL1112852)
Ki
6±n/a nM
Citation
 Sirisha, B; Narsaiah, B; Yakaiah, T; Gayatri, G; Sastry, GN; Prasad, MR; Rao, AR Synthesis and theoretical studies on energetics of novel N- and O- perfluoroalkyl triazole tagged thienopyrimidines--their potential as adenosine receptor ligands. Eur J Med Chem 45:1739-45 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50316850
Synonyms:
2-Methyl-3-prop-2-yn-1-yl-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one | CHEMBL1095695
Type:
Small organic molecule
Emp. Form.:
C13H12N2OS
Mol. Mass.:
244.312
SMILES:
Cc1nc2sc3CCCc3c2c(=O)n1CC#C
Structure:
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