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Target
Amine oxidase [flavin-containing] A
Ligand
BDBM50323856
Substrate
n/a
Meas. Tech.
ChEMBL_647382 (CHEMBL1217543)
IC50
457.73±n/a nM
Citation
 Chimenti, F; Bolasco, A; Secci, D; Chimenti, P; Granese, A; Carradori, S; Yáñez, M; Orallo, F; Ortuso, F; Alcaro, S Investigations on the 2-thiazolylhydrazyne scaffold: synthesis and molecular modeling of selective human monoamine oxidase inhibitors. Bioorg Med Chem 18:5715-23 (2010) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA)
Type:
Protein
Mol. Mass.:
59689.53
Organism:
Homo sapiens (Human)
Description:
P21397
Residue:
527
Sequence:
MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
  
Inhibitor
Name:
BDBM50323856
Synonyms:
1-(4-(3-Methoxyphenyl)thiazol-2-yl)-2-(thiophen-2-ylmethylene)hydrazine | CHEMBL1213911
Type:
Small organic molecule
Emp. Form.:
C15H13N3OS2
Mol. Mass.:
315.413
SMILES:
COc1cccc(c1)-c1csc(N=NCc2cccs2)n1 |w:13.14|
Structure:
Search PDB for entries with ligand similarity: