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Target
Phospholipid transfer protein
Ligand
BDBM50325129
Substrate
n/a
Meas. Tech.
ChEMBL_651691 (CHEMBL1228381)
IC50
60000±n/a nM
Citation
 Ling, C; Zheng, Z; Jiang, XC; Zhong, W; Li, S Synthesis of a series of novel 2,4,5-trisubstituted selenazole compounds as potential PLTP inhibitors. Bioorg Med Chem Lett 20:5123-5 (2010) [PubMed]  Article 
Target
Name:
Phospholipid transfer protein
Synonyms:
PLTP | PLTP_HUMAN
Type:
PROTEIN
Mol. Mass.:
54741.32
Organism:
Homo sapiens (Human)
Description:
ChEMBL_651691
Residue:
493
Sequence:
MALFGALFLALLAGAHAEFPGCKIRVTSKALELVKQEGLRFLEQELETITIPDLRGKEGHFYYNISEVKVTELQLTSSELDFQPQQELMLQITNASLGLRFRRQLLYWFFYDGGYINASAEGVSIRTGLELSRDPAGRMKVSNVSCQASVSRMHAAFGGTFKKVYDFLSTFITSGMRFLLNQQICPVLYHAGTVLLNSLLDTVPVRSSVDELVGIDYSLMKDPVASTSNLDMDFRGAFFPLTERNWSLPNRAVEPQLQEEERMVYVAFSEFFFDSAMESYFRAGALQLLLVGDKVPHDLDMLLRATYFGSIVLLSPAVIDSPLKLELRVLAPPRCTIKPSGTTISVTASVTIALVPPDQPEVQLSSMTMDARLSAKMALRGKALRTQLDLRRFRIYSNHSALESLALIPLQAPLKTMLQIGVMPMLNERTWRGVQIPLPEGINFVHEVVTNHAGFLTIGADLHFAKGLREVIEKNRPADVRASTAPTPSTAAV
  
Inhibitor
Name:
BDBM50325129
Synonyms:
CHEMBL1222667 | N-(5-benzyl-4-(4-hydroxyphenyl)-1,3-selenazol-2-yl)hexanamide
Type:
Small organic molecule
Emp. Form.:
C22H24N2O2Se
Mol. Mass.:
427.4
SMILES:
CCCCCC(=O)Nc1nc(c(Cc2ccccc2)[se]1)-c1ccc(O)cc1
Structure:
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