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Target
Mu-type opioid receptor
Ligand
BDBM50325534
Substrate
n/a
Meas. Tech.
ChEMBL_652218 (CHEMBL1228491)
Ki
0.582±n/a nM
Citation
 Fujii, H; Ida, Y; Hanamura, S; Osa, Y; Nemoto, T; Nakajima, M; Hasebe, K; Nakao, K; Mochizuki, H; Nagase, H Synthesis of pyrrolomorphinan derivatives as kappa opioid agonists. Bioorg Med Chem Lett 20:5035-8 (2010) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50325534
Synonyms:
CHEMBL267495 | nalfurafine
Type:
Small organic molecule
Emp. Form.:
C28H32N2O5
Mol. Mass.:
476.5641
SMILES:
CN([C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1
Structure:
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