Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50325575
Substrate
n/a
Meas. Tech.
ChEMBL_652252 (CHEMBL1225455)
Ki
35.6±n/a nM
Citation
 Lange, JH; Attali, A; van der Neut, MA; Wals, HC; Mulder, A; Zilaout, H; Duursma, A; van Aken, HH; van Vliet, BJ Two distinct classes of novel pyrazolinecarboxamides as potent cannabinoid CB1 receptor agonists. Bioorg Med Chem Lett 20:4992-8 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50325575
Synonyms:
3-butyl-4-phenyl-N-(2-phenylpropan-2-yl)-4,5-dihydro-1H-pyrazole-1-carboxamide | CHEMBL1223589
Type:
Small organic molecule
Emp. Form.:
C23H29N3O
Mol. Mass.:
363.4959
SMILES:
CCCCC1=NN(CC1c1ccccc1)C(=O)NC(C)(C)c1ccccc1 |t:4|
Structure:
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