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Target
Guanine deaminase
Ligand
BDBM82009
Substrate
n/a
Meas. Tech.
ChEMBL_652430 (CHEMBL1225633)
Ki
1960±n/a nM
Citation
 Fernández, JR; Sweet, ES; Welsh, WJ; Firestein, BL Identification of small molecule compounds with higher binding affinity to guanine deaminase (cypin) than guanine. Bioorg Med Chem 18:6748-55 (2010) [PubMed]  Article 
Target
Name:
Guanine deaminase
Synonyms:
GAH | GDA | GUAD_HUMAN | Guanase | Guanine aminase | Guanine aminohydrolase | KIAA1258 | p51-nedasin
Type:
PROTEIN
Mol. Mass.:
50993.86
Organism:
Homo sapiens (Human)
Description:
ChEMBL_885179
Residue:
454
Sequence:
MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCFKPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFAEEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEYKETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV
  
Inhibitor
Name:
BDBM82009
Synonyms:
CAS_1188 | CHEMBL1424 | NSC_1188 | Xanthine
Type:
Small organic molecule
Emp. Form.:
C5H4N4O2
Mol. Mass.:
152.1109
SMILES:
O=c1[nH]c2nc[nH]c2c(=O)[nH]1
Structure:
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