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Target
Tyrosine-protein kinase Fyn
Ligand
BDBM50298225
Substrate
n/a
Meas. Tech.
ChEMBL_660473 (CHEMBL1250103)
IC50
1000±n/a nM
Citation
 Saghatelian, A; Cravatt, BF Assignment of protein function in the postgenomic era. Nat Chem Biol 1:130-42 (2006) [PubMed]  Article 
Target
Name:
Tyrosine-protein kinase Fyn
Synonyms:
FYN | FYN_HUMAN | Proto-oncogene Syn | Proto-oncogene c-Fyn | SLK | SRC | Src-like kinase | p59-Fyn
Type:
Enzyme
Mol. Mass.:
60762.21
Organism:
Homo sapiens (Human)
Description:
P06241
Residue:
537
Sequence:
MGCVQCKDKEATKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQPGENL
  
Inhibitor
Name:
BDBM50298225
Synonyms:
CHEMBL2069955 | CHEMBL573578 | NM-PP1 | US10544104, Compound 5d | US11247972, Compound 5d | US9765037, Compound 5d
Type:
Small organic molecule
Emp. Form.:
C20H21N5
Mol. Mass.:
331.4142
SMILES:
CC(C)(C)n1nc(Cc2cccc3ccccc23)c2c(N)ncnc12
Structure:
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