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Target
Cytochrome c oxidase subunit 1
Ligand
BDBM50326830
Substrate
n/a
Meas. Tech.
ChEMBL_662814 (CHEMBL1252214)
IC50
65550±n/a nM
Citation
 Zarghi, A; Ghodsi, R Design, synthesis, and biological evaluation of ketoprofen analogs as potent cyclooxygenase-2 inhibitors. Bioorg Med Chem 18:5855-60 (2010) [PubMed]  Article 
Target
Name:
Cytochrome c oxidase subunit 1
Synonyms:
COI | COX1_SHEEP | COXI | MT-CO1 | MTCO1
Type:
PROTEIN
Mol. Mass.:
57042.19
Organism:
Ovis aries
Description:
ChEMBL_662814
Residue:
514
Sequence:
MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMIFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
  
Inhibitor
Name:
BDBM50326830
Synonyms:
2-(4-azido)phenyl)-8-benzoyl-quinoline-4-carboxylic acid | CHEMBL1254872
Type:
Small organic molecule
Emp. Form.:
C23H14N4O3
Mol. Mass.:
394.3823
SMILES:
OC(=O)c1cc(nc2c(cccc12)C(=O)c1ccccc1)-c1ccc(cc1)N=[N+]=[N-]
Structure:
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