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Target
Delta-type opioid receptor
Ligand
BDBM50290872
Substrate
n/a
Meas. Tech.
ChEMBL_674208 (CHEMBL1274305)
Ki
1.44±n/a nM
Citation
 Nagase, H; Nemoto, T; Matsubara, A; Saito, M; Yamamoto, N; Osa, Y; Hirayama, S; Nakajima, M; Nakao, K; Mochizuki, H; Fujii, H Design and synthesis of KNT-127, ad-opioid receptor agonist effective by systemic administration. Bioorg Med Chem Lett 20:6302-5 (2010) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50290872
Synonyms:
(-)-rel-3-((4aR,12aS)-2-methyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol | 3-((4aS,12aR)-2-Methyl-1,3,4,5,12,12a-hexahydro-2H-2,6-diaza-naphthacen-4a-yl)-phenol | CHEMBL327745 | SB-213698 | TAN-67 | Tan-67 (racemic)
Type:
Small organic molecule
Emp. Form.:
C23H24N2O
Mol. Mass.:
344.4495
SMILES:
CN1CC[C@@]2(Cc3nc4ccccc4cc3C[C@H]2C1)c1cccc(O)c1 |r|
Structure:
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