Target
Carbonic anhydrase 7
Ligand
BDBM50329770
Substrate
n/a
Meas. Tech.
ChEMBL_674744 (CHEMBL1273997)
Kd
830±n/a nM
Citation
 Sudžius, JBaranauskiene, LGolovenko, DMatuliene, JMichailoviene, VTorresan, JJachno, JSukackaite, RManakova, EGražulis, STumkevičius, SMatulis, D 4-[N-(substituted 4-pyrimidinyl)amino]benzenesulfonamides as inhibitors of carbonic anhydrase isozymes I, II, VII, and XIII. Bioorg Med Chem 18:7413-21 (2010) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50329770
Synonyms:
4-{[(6-methoxy-5-nitropyrimidin-4-yl)amino]methyl}benzenesulfonamide | 4-{[N-(6-Methoxy-5-nitropyrimidin-4-yl)amino]methyl}benzenesulfonamide | CHEMBL1233725
Type:
Small organic molecule
Emp. Form.:
C12H13N5O5S
Mol. Mass.:
339.327
SMILES:
COc1ncnc(NCc2ccc(cc2)S(N)(=O)=O)c1[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: