Reaction Details Report a problem with these data
Target
Carbonic anhydrase 13
Ligand
BDBM50329770
Substrate
n/a
Meas. Tech.
ChEMBL_674746 (CHEMBL1273999)
Kd
67±n/a nM
Citation
 Sudžius, J; Baranauskiene, L; Golovenko, D; Matuliene, J; Michailoviene, V; Torresan, J; Jachno, J; Sukackaite, R; Manakova, E; Gražulis, S; Tumkevičius, S; Matulis, D 4-[N-(substituted 4-pyrimidinyl)amino]benzenesulfonamides as inhibitors of carbonic anhydrase isozymes I, II, VII, and XIII. Bioorg Med Chem 18:7413-21 (2010) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 13
Synonyms:
CA13 | CAH13_HUMAN | Carbonic anhydrase | Carbonic anhydrase 13 (CA XIII) | Carbonic anhydrase XIII (CA XIII)
Type:
Enzyme
Mol. Mass.:
29445.78
Organism:
Homo sapiens (Human)
Description:
Q8N1Q1
Residue:
262
Sequence:
MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH
  
Inhibitor
Name:
BDBM50329770
Synonyms:
4-{[(6-methoxy-5-nitropyrimidin-4-yl)amino]methyl}benzenesulfonamide | 4-{[N-(6-Methoxy-5-nitropyrimidin-4-yl)amino]methyl}benzenesulfonamide | CHEMBL1233725
Type:
Small organic molecule
Emp. Form.:
C12H13N5O5S
Mol. Mass.:
339.327
SMILES:
COc1ncnc(NCc2ccc(cc2)S(N)(=O)=O)c1[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: