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Target
Low molecular weight protein-tyrosine phosphatase A
Ligand
BDBM50331863
Substrate
n/a
Meas. Tech.
ChEMBL_686940 (CHEMBL1291351)
Ki
8000±n/a nM
Citation
 Chandra, K; Dutta, D; Das, AK; Basak, A Design, synthesis and inhibition activity of novel cyclic peptides against protein tyrosine phosphatase A from Mycobacterium tuberculosis. Bioorg Med Chem 18:8365-73 (2010) [PubMed]  Article 
Target
Name:
Low molecular weight protein-tyrosine phosphatase A
Synonyms:
PTPA_MYCTU | PTPase | Probable low molecular weight protein-tyrosine-phosphatase | Protein Tyrosine Phosphatase PTPA | mptpA | ptpA
Type:
Hydrolase
Mol. Mass.:
17891.84
Organism:
Mycobacterium tuberculosis
Description:
n/a
Residue:
163
Sequence:
MSDPLHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWHVGSCADERAAGVLRAHGYPTDHRAAQVGTEHLAADLLVALDRNHARLLRQLGVEAARVRMLRSFDPRSGTHALDVEDPYYGDHSDFEEVFAVIESALPGLHDWVDERLARNGPS
  
Inhibitor
Name:
BDBM50331863
Synonyms:
6-(4-Hydroxy-benzyl)-9-(phenyl-phenylamino-methyl)-[1,4,7]triazecane-2,5,8-trione | CHEMBL1289670
Type:
Small organic molecule
Emp. Form.:
C27H28N4O4
Mol. Mass.:
472.5356
SMILES:
Oc1ccc(C[C@@H]2NC(=O)[C@H](CNC(=O)CNC2=O)[C@@H](Nc2ccccc2)c2ccccc2)cc1 |r|
Structure:
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