Reaction Details Report a problem with these data
Target
Phospholipase C
Ligand
BDBM50332115
Substrate
n/a
Meas. Tech.
ChEMBL_687789 (CHEMBL1291297)
Ki
2500±n/a nM
Citation
 González-Bulnes, P; González-Roura, A; Canals, D; Delgado, A; Casas, J; Llebaria, A 2-aminohydroxamic acid derivatives as inhibitors of Bacillus cereus phosphatidylcholine preferred phospholipase C PC-PLC(Bc). Bioorg Med Chem 18:8549-55 (2010) [PubMed]  Article 
Target
Name:
Phospholipase C
Synonyms:
Cereolysin A | PHLC_BACCE | Phosphatidylcholine cholinephosphohydrolase | plc
Type:
PROTEIN
Mol. Mass.:
32387.39
Organism:
Bacillus cereus
Description:
ChEMBL_687786
Residue:
283
Sequence:
MKKKVLALAAAITVVAPLQSVAFAHENDGGSKIKIVHRWSAEDKHKEGVNSHLWIVNRAIDIMSRNTTLVKQDRVAQLNEWRTELENGIYAADYENPYYDNSTFASHFYDPDNGKTYIPFAKQAKETGAKYFKLAGESYKNKDMKQAFFYLGLSLHYLGDVNQPMHAANFTNLSYPQGFHSKYENFVDTIKDNYKVTDGNGYWNWKGTNPEEWIHGAAVVAKQDYSGIVNDNTKDWFVKAAVSQEYADKWRAEVTPMTGKRLMDAQRVTAGYIQLWFDTYGDR
  
Inhibitor
Name:
BDBM50332115
Synonyms:
3-(N-(benzyloxy)-2-(tert-butyloxycarbonylamino)dodecanamido-N,N,N-trimethylpropan-1-aminium iodide | CHEMBL1287946
Type:
Small organic molecule
Emp. Form.:
C30H54N3O4
Mol. Mass.:
520.7669
SMILES:
CCCCCCCCCCC(NC(=O)OC(C)(C)C)C(=O)N(CCC[N+](C)(C)C)OCc1ccccc1
Structure:
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