Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50332880
Substrate
n/a
Meas. Tech.
ChEMBL_694006 (CHEMBL1636582)
Ki
495.3±n/a nM
Citation
 Silvestri, R; Ligresti, A; La Regina, G; Piscitelli, F; Gatti, V; Lavecchia, A; Brizzi, A; Pasquini, S; Allarà, M; Fantini, N; Carai, MA; Bigogno, C; Rozio, MG; Sinisi, R; Novellino, E; Colombo, G; Di Marzo, V; Dondio, G; Corelli, F Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands. Eur J Med Chem 45:5878-86 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50332880
Synonyms:
1-(2,4-Dichlorophenyl)-5-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methyl-N-pentyl-1H-pyrazole-3-carboxamide | CHEMBL1631168
Type:
Small organic molecule
Emp. Form.:
C22H26Cl2N4O
Mol. Mass.:
433.374
SMILES:
CCCCCNC(=O)c1nn(c(c1C)-n1c(C)ccc1C)-c1ccc(Cl)cc1Cl |(21.54,-1.2,;20.8,.15,;19.27,.19,;18.54,1.55,;16.99,1.58,;16.26,2.92,;14.72,2.97,;13.99,4.3,;13.82,1.72,;14.3,.28,;13.07,-.64,;11.81,.25,;12.28,1.72,;11.37,2.97,;10.35,-.23,;9.89,-1.69,;10.68,-2.81,;8.34,-1.7,;7.86,-.24,;9.08,.67,;9.07,2.21,;13.09,-2.18,;11.76,-2.97,;11.78,-4.51,;13.12,-5.27,;13.13,-6.81,;14.45,-4.49,;14.43,-2.94,;15.76,-2.15,)|
Structure:
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