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Target
Matrix metalloproteinase-14
Ligand
BDBM50264809
Substrate
n/a
Meas. Tech.
ChEMBL_702136 (CHEMBL1655473)
Ki
110±n/a nM
Citation
 Testero, SA; Lee, M; Staran, RT; Espahbodi, M; Llarrull, LI; Toth, M; Mobashery, S Sulfonate-Containing Thiiranes as Selective Gelatinase Inhibitors ACS Med Chem Lett 2:177-181 (2011) [PubMed]  Article 
Target
Name:
Matrix metalloproteinase-14
Synonyms:
MMP-14 | MMP-X1 | MMP14 | MMP14_HUMAN | MT-MMP 1 | MT1-MMP | MT1MMP | MTMMP1 | Matrix Metalloproteinase-14 (MMP-14) | Matrix metalloproteinase 14 | Matrix metalloproteinase-14 | Matrix metalloproteinase-14 (MMP14) | Membrane-type matrix metalloproteinase 1 | Membrane-type-1 matrix metalloproteinase
Type:
Protein
Mol. Mass.:
65900.19
Organism:
Homo sapiens (Human)
Description:
P50281
Residue:
582
Sequence:
MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPRTTSRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV
  
Inhibitor
Name:
BDBM50264809
Synonyms:
2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEMBL483857 | Thiirane (deuterium), 1-d2 | Thiirane, 1 | US10357546, SB-3CT
Type:
Small organic molecule
Emp. Form.:
C15H14O3S2
Mol. Mass.:
306.4
SMILES:
O=S(=O)(CC1CS1)c1ccc(Oc2ccccc2)cc1
Structure:
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