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Target
Telomere resolvase ResT
Ligand
BDBM50335562
Substrate
n/a
Meas. Tech.
ChEMBL_713937 (CHEMBL1660353)
IC50
2620±n/a nM
Citation
 Lefas, G; Chaconas, G High-throughput screening identifies three inhibitor classes of the telomere resolvase from the lyme disease spirochete. Antimicrob Agents Chemother 53:4441-9 (2009) [PubMed]  Article 
Target
Name:
Telomere resolvase ResT
Synonyms:
REST_BORBU | resT
Type:
PROTEIN
Mol. Mass.:
54325.70
Organism:
Borrelia burgdorferi
Description:
ChEMBL_713937
Residue:
449
Sequence:
MPPKVKIKNDFEIFRKELEILYKKYLNNELSYLKLKEKLKILAENHKAILFRKDKFTNRSIILNLSKTRKIIKEYINLSVIERIRRDNTFLFFWKSRRIKELKNIGIKDRKKIEELIFSNQMNDEKSYFQYFIDLFVTPKWLNDYAHKYKIEKINSYRKEQIFVKINLNTYIEIIKLLLNQSRDIRLKFYGVLMAIGRRPVEVMKLSQFYIADKNHIRMEFIAKKRENNIVNEVVFPVFADPELIINSIKEIRYMEQTENLTKEIISSNLAYSYNRLFRQIFNNIFAPEESVYFCRAIYCKFSYLAFAPKNMEMNYWITKVLGHEPNDITTAFHYNRYVLDNLDDKADNSLLTLLNQRIYTYVRRKATYSTLTMDRLESLIKEHHIFDDNYIKTLIVIKNLMLKDNLETLAMVRGLNVKIRKAFKATYGYNYNYIKLTEYLSIIFNYKL
  
Inhibitor
Name:
BDBM50335562
Synonyms:
13-(cyclopent-2-enyl)tridecanoic acid | CHEMBL1649743
Type:
Small organic molecule
Emp. Form.:
C18H32O2
Mol. Mass.:
280.4455
SMILES:
OC(=O)CCCCCCCCCCCCC1CCC=C1 |c:18|
Structure:
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