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Target
Melatonin receptor type 1A
Ligand
BDBM50340328
Substrate
n/a
Meas. Tech.
ChEMBL_740913 (CHEMBL1764014)
EC50
93±n/a nM
Citation
 Jeanty, M; Suzenet, F; Delagrange, P; Nosjean, O; Boutin, JA; Caignard, DH; Guillaumet, G Design and synthesis of 1-(2-alkanamidoethyl)-6-methoxy-7-azaindole derivatives as potent melatonin agonists. Bioorg Med Chem Lett 21:2316-9 (2011) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50340328
Synonyms:
CHEMBL1760955 | N-(2-(6-methoxy-3-(2,2,2-trifluoroacetyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)ethyl)acetamide
Type:
Small organic molecule
Emp. Form.:
C14H14F3N3O3
Mol. Mass.:
329.2745
SMILES:
COc1ccc2c(cn(CCNC(C)=O)c2n1)C(=O)C(F)(F)F
Structure:
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