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Target
Oxoeicosanoid receptor 1
Ligand
BDBM50341133
Substrate
n/a
Meas. Tech.
ChEMBL_740370 (CHEMBL1764428)
IC50
7.5±n/a nM
Citation
 Patel, P; Gore, V; Powell, WS; Rokach, J C20-trifluoro-5-oxo-ETE: a metabolically stable 5-oxo-ETE derivative. Bioorg Med Chem Lett 21:1987-90 (2011) [PubMed]  Article 
Target
Name:
Oxoeicosanoid receptor 1
Synonyms:
5-oxo-ETE G-protein coupled receptor | G-protein coupled receptor 170 | G-protein coupled receptor R527 | G-protein coupled receptor TG1019 | GPR170 | OXER1 | OXER1_HUMAN | Oxoeicosanoid receptor 1 | TG 1019 | TG1019
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45833.20
Organism:
Homo sapiens (Human)
Description:
TG 1019 0 HUMAN::Q8TDS5
Residue:
423
Sequence:
MLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPSFSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGSSQG
  
Inhibitor
Name:
BDBM50341133
Synonyms:
(6E,8Z,11Z,14Z)-20,20,20-trifluoro-5-oxoicosa-6,8,11,14-tetraenoic acid | CHEMBL1760545
Type:
Small organic molecule
Emp. Form.:
C20H27F3O3
Mol. Mass.:
372.4218
SMILES:
OC(=O)CCCC(=O)C=CC=CC\C=C/C\C=C/CCCCC(F)(F)F |w:9.9,11.11|
Structure:
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