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Target
Triosephosphate isomerase
Ligand
BDBM50167777
Substrate
n/a
Meas. Tech.
ChEMBL_744985 (CHEMBL1772000)
Ki
4000±n/a nM
Citation
 Yep, A; Sorenson, RJ; Wilson, MR; Showalter, HD; Larsen, SD; Keller, PR; Woodard, RW Enediol mimics as inhibitors of the D-arabinose 5-phosphate isomerase (KdsD) from Francisella tularensis. Bioorg Med Chem Lett 21:2679-82 (2011) [PubMed]  Article 
Target
Name:
Triosephosphate isomerase
Synonyms:
TIM | TPI | TPI1 | TPIS_HUMAN | Triose-phosphate isomerase | Triosephosphate isomerase | Triosephosphate isomerase (TIM)
Type:
Enzyme
Mol. Mass.:
30788.11
Organism:
Homo sapiens (Human)
Description:
P60174
Residue:
249
Sequence:
MAPSRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ
  
Inhibitor
Name:
BDBM50167777
Synonyms:
2-(hydroxyamino)-2-oxoethyl dihydrogen phosphate | CHEMBL371668 | Phosphoglycolohydroxamic Acid
Type:
Small organic molecule
Emp. Form.:
C2H6NO6P
Mol. Mass.:
171.0459
SMILES:
ONC(=O)COP(O)(O)=O
Structure:
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