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Target
Arabinose 5-phosphate isomerase KdsD
Ligand
BDBM50148780
Substrate
n/a
Meas. Tech.
ChEMBL_744987 (CHEMBL1772002)
IC50
3000000±n/a nM
Citation
 Yep, A; Sorenson, RJ; Wilson, MR; Showalter, HD; Larsen, SD; Keller, PR; Woodard, RW Enediol mimics as inhibitors of the D-arabinose 5-phosphate isomerase (KdsD) from Francisella tularensis. Bioorg Med Chem Lett 21:2679-82 (2011) [PubMed]  Article 
Target
Name:
Arabinose 5-phosphate isomerase KdsD
Synonyms:
Arabinose phosphate isomerase | KDSD_FRATT | kdsD
Type:
PROTEIN
Mol. Mass.:
35692.42
Organism:
Francisella tularensis subsp. tularensis
Description:
ChEMBL_744987
Residue:
327
Sequence:
MEISMTSHINNAVETFRLEIETLEKLKNSIDENFEKACEIILENNRDKSRVIITGMGKSGHIGKKMAATFASTGTPAFFVHPGEAGHGDFGMITKNDVLIAISNSGTSSEIMGLLPMIKHLDIPIIAITSNPKSILARNSNVTLNLHVDKEACPLNLAPTSSTTATLVLGDALAIALLKAKNFSEKDFAFSHPNGALGRKLILKVENIMRKGNEIPIVKPTDNIRKAILEISDKGVGNTLVAENNTLLGIFTDGDLRRMFEAESFNSQRAISEVMTKNPKSISKEEMAITALEKMEKYEITSLAVVDNGHNILGIVTMHDLIKLELR
  
Inhibitor
Name:
BDBM50148780
Synonyms:
((4R,5R)-5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl dihydrogen phosphate | (5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl dihydrogen phosphate | CHEMBL324609 | Phosphoric acid mono-((R)-(R)-5-hydroxycarbamoyl-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl) ester
Type:
Small organic molecule
Emp. Form.:
C7H14NO8P
Mol. Mass.:
271.1617
SMILES:
CC1(C)O[C@H](COP(O)(O)=O)[C@@H](O1)C(=O)NO
Structure:
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