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Target
Arabinose 5-phosphate isomerase KdsD
Ligand
BDBM50148765
Substrate
n/a
Meas. Tech.
ChEMBL_744987 (CHEMBL1772002)
IC50
7000±n/a nM
Citation
 Yep, A; Sorenson, RJ; Wilson, MR; Showalter, HD; Larsen, SD; Keller, PR; Woodard, RW Enediol mimics as inhibitors of the D-arabinose 5-phosphate isomerase (KdsD) from Francisella tularensis. Bioorg Med Chem Lett 21:2679-82 (2011) [PubMed]  Article 
Target
Name:
Arabinose 5-phosphate isomerase KdsD
Synonyms:
Arabinose phosphate isomerase | KDSD_FRATT | kdsD
Type:
PROTEIN
Mol. Mass.:
35692.42
Organism:
Francisella tularensis subsp. tularensis
Description:
ChEMBL_744987
Residue:
327
Sequence:
MEISMTSHINNAVETFRLEIETLEKLKNSIDENFEKACEIILENNRDKSRVIITGMGKSGHIGKKMAATFASTGTPAFFVHPGEAGHGDFGMITKNDVLIAISNSGTSSEIMGLLPMIKHLDIPIIAITSNPKSILARNSNVTLNLHVDKEACPLNLAPTSSTTATLVLGDALAIALLKAKNFSEKDFAFSHPNGALGRKLILKVENIMRKGNEIPIVKPTDNIRKAILEISDKGVGNTLVAENNTLLGIFTDGDLRRMFEAESFNSQRAISEVMTKNPKSISKEEMAITALEKMEKYEITSLAVVDNGHNILGIVTMHDLIKLELR
  
Inhibitor
Name:
BDBM50148765
Synonyms:
1-(hydroxyamino)-1-oxo-4-(phosphonooxy)butane-2,3-diyl diacetate | Acetic acid (1R,3R)-2-acetoxy-1-hydroxycarbamoyl-3-phosphonooxy-propyl ester | CHEMBL114269
Type:
Small organic molecule
Emp. Form.:
C8H14NO10P
Mol. Mass.:
315.1712
SMILES:
CC(=O)O[C@H](COP(O)(O)=O)[C@@H](OC(C)=O)C(=O)NO
Structure:
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