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Target
Melatonin receptor type 1B
Ligand
BDBM50342771
Substrate
n/a
Meas. Tech.
ChEMBL_744408 (CHEMBL1772362)
IC50
97±n/a nM
Citation
 Leclerc, V; Ettaoussi, M; Rami, M; Farce, A; Boutin, JA; Delagrange, P; Caignard, DH; Renard, P; Berthelot, P; Yous, S Design and synthesis of naphthalenic derivatives as new ligands at the melatonin binding site MT3. Eur J Med Chem 46:1622-9 (2011) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50342771
Synonyms:
CHEMBL456646 | N-(2-(7-(methylsulfinyl)naphthalen-1-yl)ethyl)acetamide | N-[2-(7-methylsulfinyl-naphth-1-yl)ethyl]acetamide
Type:
Small organic molecule
Emp. Form.:
C15H17NO2S
Mol. Mass.:
275.366
SMILES:
CC(=O)NCCc1cccc2ccc(cc12)S(C)=O
Structure:
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